Treatment of persistent pruritus ani in a combined colorectal and dermatological clinic

Br J Surg. 1999 Oct;86(10):1337-40. doi: 10.1046/j.1365-2168.1999.01231.x.

Abstract

Background: Pruritus ani is a common and socially embarrassing condition which is often poorly managed. It is often classified as idiopathic where the symptoms are usually transitory or secondary when a more persistent itch is experienced. The aim of this study was to establish the cause of pruritus ani in a group of patients referred to a combined colorectal and dermatological clinic, and to determine the most appropriate treatment.

Methods: Forty consecutive patients with pruritus ani were referred over a 6-month period from either the general practitioner or another hospital consultant to a combined colorectal and dermatological clinic. They were assessed by history, completion of a general health questionnaire, full examination of the skin, digital rectal examination, proctoscopy, sigmoidoscopy and patch testing. Patients were treated according to clinical findings at assessment.

Results: Thirty-four patients had a recognizable dermatosis, three had superficial perianal fissuring and three had a normal perineum; two required surgical intervention. Eighteen patients had a positive reaction when patch tested. All patients have shown an improvement or complete resolution of symptoms with treatment.

Conclusion: This series has shown that the majority of patients presenting with pruritus ani have a dermatosis as the underlying cause of their symptoms and that many of them have developed contact sensitivities to the various topical medications used. These findings suggest that referral to a dermatologist in the first instance may be more appropriate.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-Inflammatory Agents / therapeutic use
  • Female
  • Follow-Up Studies
  • Humans
  • Hydrocortisone / therapeutic use
  • Male
  • Middle Aged
  • Patch Tests
  • Pruritus Ani / drug therapy*
  • Time Factors

Substances

  • Anti-Inflammatory Agents
  • Hydrocortisone