Objective: To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people.
Method: We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method.
Results: There was no difference in the IL10R genotype frequencies of these two groups.
Conclusion: The IL10R genotype does not determine susceptibility to SLE in Japanese people.