Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with Alzheimer's disease

S Sevush; G Peruyera; F Crawford; M Mullan

Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with Alzheimer's disease

Am J Geriatr Psychiatry. 2000 Summer;8(3):254-6.

Authors

S Sevush¹, G Peruyera, F Crawford, M Mullan

Affiliation

¹ Department of Psychiatry, University of Miami School of Medicine, FL 33136, USA.

PMID: 10910426

Abstract

The authors compared Apo-E epsilon 4 frequencies for Cuban American and white non-Hispanic persons with and without Alzheimer's disease (AD). The Apo-E epsilon 4 allele conferred as large a risk for AD in Cuban Americans as for white non-Hispanics, a finding that differs from those for Hispanic subjects as a whole.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Alleles
Alzheimer Disease / ethnology*
Alzheimer Disease / genetics*
Apolipoprotein E4
Apolipoproteins E / genetics*
Case-Control Studies
Cuba / ethnology
Female
Florida
Genotype
Hispanic or Latino / genetics*
Humans
Male
Middle Aged
Polymerase Chain Reaction
White People / genetics

Substances

Apolipoprotein E4
Apolipoproteins E