Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia

Leukemia. 2000 Jul;14(7):1314-5. doi: 10.1038/sj.leu.2401782.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Anemia, Refractory, with Excess of Blasts / chemically induced
  • Anemia, Refractory, with Excess of Blasts / drug therapy
  • Anemia, Refractory, with Excess of Blasts / etiology*
  • Anemia, Refractory, with Excess of Blasts / genetics
  • Aneuploidy
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Asparaginase / administration & dosage
  • Asparaginase / adverse effects
  • Child
  • Chromosome Aberrations*
  • Chromosomes, Human, Pair 8 / genetics*
  • Cladribine / administration & dosage
  • Combined Modality Therapy
  • Cranial Irradiation / adverse effects*
  • Cytarabine / administration & dosage
  • Cytarabine / adverse effects
  • Daunorubicin / administration & dosage
  • Daunorubicin / adverse effects
  • Fatal Outcome
  • Female
  • Gene Amplification*
  • Genes, myc*
  • Humans
  • Hydrocortisone / administration & dosage
  • Hydrocortisone / adverse effects
  • Karyotyping
  • Mercaptopurine / administration & dosage
  • Mercaptopurine / adverse effects
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / therapy*
  • Prednisone / administration & dosage
  • Prednisone / adverse effects
  • Vincristine / administration & dosage
  • Vincristine / adverse effects

Substances

  • Cytarabine
  • Cladribine
  • Vincristine
  • Mercaptopurine
  • Asparaginase
  • Prednisone
  • Hydrocortisone
  • Daunorubicin