Abstract
A 66-year-old female who presented with cervical lymphadenopathy and splenomegaly was found to have large B-cell lymphoma on lymph node biopsy. However, trephine biopsy revealed involvement of the marrow by follicular lymphoma, and cytogenetic study showed an abnormal clone with 47,XX,+18.
MeSH terms
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Aged
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Chromosomes, Human, Pair 14 / genetics
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Chromosomes, Human, Pair 18 / genetics*
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Female
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Humans
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Immunohistochemistry
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Karyotyping
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Lymphoma, Follicular / genetics*
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Lymphoma, Follicular / pathology
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Proto-Oncogene Proteins c-bcl-2 / biosynthesis*
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Translocation, Genetic
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Trisomy*
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Uterine Cervical Neoplasms / genetics*
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Uterine Cervical Neoplasms / pathology
Substances
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Proto-Oncogene Proteins c-bcl-2