Abstract
We postulate that oncogenes and tumor suppressor genes may influence tumor angiogenesis not only directly (e.g. by upregulating vascular endothelial growth factor) but also through their impact on expression (and/or function) of tissue factor and other elements of the hemostatic system.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Gene Expression Regulation, Neoplastic
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Genes, Tumor Suppressor*
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Hemostasis / genetics
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Hemostasis / physiology*
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Humans
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Neoplasms / blood
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Neoplasms / blood supply
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Neoplasms / genetics*
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Neovascularization, Pathologic / genetics
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Neovascularization, Pathologic / physiopathology*
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Oncogenes*