Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorder

Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):71S-75S. doi: 10.1097/00000374-200105051-00013.

Abstract

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Shoji Harada and Dharam P. Agarwal. The presentations were (1) Mutations in the exons, exon-intron junctions, and promoter regions of human CYP2E1 gene and alcoholism, by Fumio Nomura; (2) Genetic variability in alcohol metabolism and drinking habits in Japanese, by Shoji Harada; (3) Genetic studies of alcohol dependence using alcoholics with inactive ALDH2, by Susumu Higuchi; and (4) Alcohol consumption, apolipoprotein polymorphisms, and cardiovascular disorders, by Dharam P. Agarwal.

Publication types

  • Review

MeSH terms

  • Alcohol Drinking / genetics*
  • Alcohol Drinking / metabolism
  • Alcohol-Related Disorders / genetics*
  • Alcohol-Related Disorders / metabolism
  • Aldehyde Dehydrogenase / genetics*
  • Aldehyde Dehydrogenase / metabolism
  • Aldehyde Dehydrogenase, Mitochondrial
  • Animals
  • Apolipoproteins / genetics*
  • Apolipoproteins / metabolism
  • Cardiovascular Diseases / genetics
  • Cardiovascular Diseases / metabolism
  • Cytochrome P-450 CYP2E1 / genetics*
  • Cytochrome P-450 CYP2E1 / metabolism
  • Humans
  • Japan / ethnology
  • Polymorphism, Genetic / genetics
  • Receptor, Serotonin, 5-HT1B
  • Receptors, Serotonin / genetics

Substances

  • Apolipoproteins
  • HTR1B protein, human
  • Receptor, Serotonin, 5-HT1B
  • Receptors, Serotonin
  • Cytochrome P-450 CYP2E1
  • ALDH2 protein, human
  • Aldehyde Dehydrogenase
  • Aldehyde Dehydrogenase, Mitochondrial