Abstract
The Escherichia coli zitB gene encodes a Zn(II) transporter belonging to the cation diffusion facilitator family. ZitB is specifically induced by zinc. ZitB expression on a plasmid rendered zntA-disrupted E. coli cells more resistant to zinc, and the cells exhibited reduced accumulation of (65)Zn, suggesting ZitB-mediated efflux of zinc.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacterial Proteins / genetics
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Bacterial Proteins / physiology*
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Carrier Proteins / genetics
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Carrier Proteins / physiology*
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Cations
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Escherichia coli / drug effects
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Escherichia coli / genetics
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Escherichia coli / metabolism
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Homeostasis
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Metals / pharmacology
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Zinc / metabolism*
Substances
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Bacterial Proteins
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Carrier Proteins
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Cations
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Metals
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zinc-binding protein
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Zinc