[The evaluation of VNTR-polymorphism in the gene of dopamine transporter in men of different nationalities with acute alcoholic psychosis]

Zh Nevrol Psikhiatr Im S S Korsakova. 2001;101(5):43-5.
[Article in Russian]

Abstract

VNTR-polymorphism of the gene of dopamine transporter (DAT) in men of the Russian and Tatar nationalities with acute alcoholic psychoses was analyzed by method of the polymerase chain reaction. There were no differences in the distribution of frequencies of genotypes and alleles of DAT gene between the populations examined. There was association between an allele variant with 9 units of DAT gene repetition (in homozygous state first of all), and early development of alcoholic dependence and acute alcoholic psychosis.

Publication types

  • English Abstract

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Biological Transport / physiology
  • Carrier Proteins / genetics*
  • Carrier Proteins / metabolism*
  • Dopamine / genetics*
  • Dopamine / metabolism*
  • Gene Expression / genetics*
  • Gene Frequency
  • Humans
  • Male
  • Middle Aged
  • Minisatellite Repeats / genetics*
  • Psychoses, Alcoholic* / ethnology*
  • Psychoses, Alcoholic* / genetics*
  • Russia / epidemiology

Substances

  • Carrier Proteins
  • Dopamine