The 677C-->T mutation of the methylene-tetrahydrofolate reductase gene in the pathogenesis of osteonecrosis of the femoral head

Haematologica. 2002 Jan;87(1):111-2.
No abstract available

MeSH terms

  • Adult
  • Alleles
  • Amino Acid Substitution*
  • Codon / genetics
  • Female
  • Femur Head Necrosis / genetics*
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Greece / epidemiology
  • Homozygote
  • Humans
  • Hyperhomocysteinemia / genetics
  • Male
  • Methylenetetrahydrofolate Reductase (NADPH2)
  • Mutation, Missense*
  • Oxidoreductases Acting on CH-NH Group Donors / deficiency
  • Oxidoreductases Acting on CH-NH Group Donors / genetics*
  • Point Mutation*
  • Risk Factors
  • Thrombophilia / genetics

Substances

  • Codon
  • Oxidoreductases Acting on CH-NH Group Donors
  • Methylenetetrahydrofolate Reductase (NADPH2)