Abstract
An association between the cytosolic phospholipase A2 locus (cPLA2) and schizophrenia has been reported using two polymorphic DNA markers. In an attempt to replicate these results, two independent family-based samples were ascertained from the United States and India (86 and 159 families, respectively). No significant associations were detected in either sample.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Base Sequence
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Black People / genetics
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Chi-Square Distribution
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Cytosol / enzymology
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DNA Primers
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Family
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Gene Frequency
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Genotype
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Group IV Phospholipases A2
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Humans
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Phospholipases A / genetics*
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Phospholipases A2
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Poly A / genetics
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Polymerase Chain Reaction
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Polymorphism, Genetic*
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Schizophrenia / enzymology
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Schizophrenia / genetics*
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United States
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White People / genetics
Substances
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DNA Primers
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Poly A
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Phospholipases A
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Group IV Phospholipases A2
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Phospholipases A2