The enigmatic Escherichia coli fadE gene is yafH

J Bacteriol. 2002 Jul;184(13):3759-64. doi: 10.1128/JB.184.13.3759-3764.2002.

Abstract

The identity of the gene encoding acyl coenzyme A dehydrogenase is a major remaining mystery of the Escherichia coli fatty acid degradation (fad) regulon. Our prior genome array analyses showed that transcription of the yafH gene is controlled by the FadR regulatory protein. We now report direct experimental proof that yafH and fadE are the same gene.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acyl-CoA Dehydrogenase
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Base Sequence
  • Binding Sites
  • Escherichia coli / genetics*
  • Escherichia coli Proteins / genetics*
  • Escherichia coli Proteins / metabolism*
  • Fatty Acid Desaturases / genetics*
  • Fatty Acid Desaturases / metabolism*
  • Frameshift Mutation
  • Molecular Sequence Data
  • Mutation
  • Oligonucleotide Array Sequence Analysis
  • Repressor Proteins / genetics
  • Repressor Proteins / metabolism
  • Transcription, Genetic

Substances

  • Bacterial Proteins
  • Escherichia coli Proteins
  • FadR protein, Bacteria
  • Repressor Proteins
  • Fatty Acid Desaturases
  • Acyl-CoA Dehydrogenase

Associated data

  • GENBANK/AF486265