Abstract
The lipoma preferred partner (LPP) gene is fused to the high mobility group protein gene HMGIC in lipomas and pulmonary chondroid hamartomas. In addition, a fusion of LPP to the mixed lineage leukemia (MLL) gene has been described in a case of acute myeloid leukemia. Herein, a novel LPP fusion transcript of LPP in a lipoma is described that points to the possible oncogenic potential of LPP.
Copyright 2002 S. Karger AG, Basel
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Amino Acid Sequence
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Base Sequence
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Cytoskeletal Proteins / genetics*
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Female
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Hamartoma / genetics*
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High Mobility Group Proteins / genetics*
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Humans
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LIM Domain Proteins
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Lipoma / genetics*
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Lung Neoplasms / genetics*
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Molecular Sequence Data
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Oncogene Proteins, Fusion
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RNA Splice Sites / genetics
Substances
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Cytoskeletal Proteins
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High Mobility Group Proteins
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LIM Domain Proteins
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LPP protein, human
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Oncogene Proteins, Fusion
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RNA Splice Sites