[Frequencies distribution of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations]

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Feb;20(1):9-11.
[Article in Chinese]

Abstract

Objective: To investigate the frequencies distribution of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations.

Methods: GSTT1 and GSTM1 genotypes were analyzed by PCR procedure.

Results: The range of frequencies for GSTT1 and GSTM1 null genotypes in the populations were 0.188-0.633 and 0.400-0.745, respectively, and in the districts were 0.286-0.583, 0.433-0.745 respectively. There was significant relationship between GSTT1 frequencies and populations.

Conclusion: The frequencies of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations were different, but they were almost the same in different districts of Yunnan.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • China
  • DNA / genetics
  • Gene Frequency
  • Genotype
  • Glutathione Transferase / genetics*
  • Humans
  • Polymerase Chain Reaction

Substances

  • DNA
  • glutathione S-transferase T1
  • Glutathione Transferase
  • glutathione S-transferase M1