Abstract
We describe the case of a 57-year-old woman with a tumor of the breast suspected of being a dermatofibrosarcoma protuberans (DFSP). To confirm the diagnosis, molecular studies were performed on fixed tumor and revealed the presence of the fusion product of the COL1A1-PDGFB genes characteristic of DFSP.
MeSH terms
-
Breast Neoplasms / genetics*
-
Breast Neoplasms / pathology*
-
Breast Neoplasms / surgery
-
Collagen Type I / genetics
-
Collagen Type I, alpha 1 Chain
-
Dermatofibrosarcoma / genetics*
-
Dermatofibrosarcoma / pathology*
-
Dermatofibrosarcoma / surgery
-
Exons
-
Female
-
Humans
-
Middle Aged
-
Oncogene Proteins, Fusion / genetics
-
Receptor, Platelet-Derived Growth Factor beta / genetics
-
Skin Neoplasms / genetics*
-
Skin Neoplasms / pathology*
-
Skin Neoplasms / surgery
Substances
-
Collagen Type I
-
Collagen Type I, alpha 1 Chain
-
Oncogene Proteins, Fusion
-
Receptor, Platelet-Derived Growth Factor beta