Abstract
Aims and methods:
In the present study, differences in alcohol consumption behaviour associated with the presence of the short variant (S) of the serotonin transporter promoter polymorphism (5-HTTLPR) was investigated in a Caucasian subset (n = 204) of 268 college students.
Results:
Students who were homozygous for the S allele were more likely to engage in binge-drinking behaviour, drank more alcohol per occasion, and reported drinking to get drunk more often.
Conclusions:
In this Caucasian sample, the 5-HTTLPR strongly influences alcohol consumption in late pubescence.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Adult
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Alcohol Drinking / epidemiology
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Alcohol Drinking / genetics*
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Alcohol Drinking / psychology
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Analysis of Variance
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Carrier Proteins / genetics*
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Female
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Humans
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Least-Squares Analysis
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Male
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Membrane Glycoproteins / genetics*
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Membrane Transport Proteins*
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Nerve Tissue Proteins*
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Polymorphism, Genetic*
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Promoter Regions, Genetic*
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Serotonin Plasma Membrane Transport Proteins
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Statistics, Nonparametric
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Students* / psychology
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Students* / statistics & numerical data
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Universities / statistics & numerical data
Substances
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Carrier Proteins
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Membrane Glycoproteins
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Membrane Transport Proteins
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Nerve Tissue Proteins
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SLC6A4 protein, human
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Serotonin Plasma Membrane Transport Proteins