Focusing on foci: H2AX and the recruitment of DNA-damage response factors

Cell Cycle. 2003 Sep-Oct;2(5):426-7.

Authors

Oscar Fernandez-Capetillo¹, Arkady Celeste, André Nussenzweig

Affiliation

¹ Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1360, USA.

PMID: 12963833

No abstract available

Publication types

Review

MeSH terms

Animals
Ataxia Telangiectasia Mutated Proteins
Cell Cycle Proteins / metabolism
Cell Nucleus / metabolism
Checkpoint Kinase 2
DNA Damage / physiology*
DNA Repair / physiology*
DNA-Activated Protein Kinase
DNA-Binding Proteins*
Histones / metabolism*
Mice
Mice, Knockout
Nuclear Proteins / metabolism
Phosphorylation
Protein Serine-Threonine Kinases / metabolism
Tumor Suppressor Proteins

Substances

Cell Cycle Proteins
DNA-Binding Proteins
H2AX protein, human
Histones
NBN protein, human
Nuclear Proteins
Tumor Suppressor Proteins
Atr protein, mouse
Checkpoint Kinase 2
ATM protein, human
Ataxia Telangiectasia Mutated Proteins
Atm protein, mouse
CHEK2 protein, human
Chek2 protein, mouse
DNA-Activated Protein Kinase
Protein Serine-Threonine Kinases