Protein phosphatase X has been highly conserved during mammalian evolution

Biochim Biophys Acta. 1992 Dec 29;1171(2):231-3. doi: 10.1016/0167-4781(92)90129-n.

Abstract

Complementary DNA encoding human protein phosphatase X (PPX, also designated PPP4 in the human genome nomenclature) was isolated from a teratocarcinoma library. The deduced amino acid sequence of human PPX differs from that of rabbit PPX in only two in 307 amino acids, demonstrating that the structure of PPX has been highly conserved during the course of mammalian evolution.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Biological Evolution*
  • DNA / genetics
  • DNA, Neoplasm / genetics
  • DNA, Neoplasm / isolation & purification
  • Female
  • Gene Library
  • Humans
  • Mammals / genetics*
  • Molecular Sequence Data
  • Multigene Family*
  • Oligodeoxyribonucleotides
  • Phosphoprotein Phosphatases / genetics*
  • Phylogeny
  • Polymerase Chain Reaction / methods
  • Teratoma
  • Tumor Cells, Cultured

Substances

  • DNA, Neoplasm
  • Oligodeoxyribonucleotides
  • DNA
  • Phosphoprotein Phosphatases

Associated data

  • GENBANK/M91429
  • GENBANK/M91430
  • GENBANK/M93297
  • GENBANK/M93298
  • GENBANK/M93299
  • GENBANK/M93300
  • GENBANK/M93301
  • GENBANK/S53047
  • GENBANK/S55205
  • GENBANK/X70218