Abstract
Transgenic experimentation has become a crucial part of hypertension and atherosclerosis research, and is growing more important in several other areas of cardiovascular disease. It has recently made a particular contribution to understanding the role of the renin-angiotensin system in controlling hypertension. The study of blood pressure regulation, cardiac hypertrophy, atherogenesis and thrombosis are also benefiting from the transgenic approach.
MeSH terms
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Animals
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Animals, Genetically Modified*
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Apolipoprotein A-I / metabolism
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Arteriosclerosis / genetics
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Arteriosclerosis / physiopathology
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Blood Pressure
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Cardiomegaly / genetics
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Cardiomegaly / physiopathology
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Cardiovascular Diseases / genetics
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Cardiovascular Diseases / physiopathology*
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Cholesterol, HDL / blood
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Disease Models, Animal
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Humans
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Hypertension / genetics
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Hypertension / physiopathology
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Mice
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Mice, Transgenic
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Renin / genetics
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Renin-Angiotensin System / genetics
Substances
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Apolipoprotein A-I
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Cholesterol, HDL
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Renin