Variant translocations in two Burkitt's lymphoma cell lines are located in the MLV14 locus

M I Gallego; P A Lazo

doi:10.1002/gcc.2870050317

Variant translocations in two Burkitt's lymphoma cell lines are located in the MLV14 locus

Genes Chromosomes Cancer. 1992 Oct;5(3):267-9. doi: 10.1002/gcc.2870050317.

Authors

M I Gallego¹, P A Lazo

Affiliation

¹ Unidad de Genética Molecular, Instituto de Salud Carlos III, Majadahonda, Spain.

PMID: 1384683
DOI: 10.1002/gcc.2870050317

Abstract

The human MLV14 locus, located 20 kilobases 3' of MYC, is rearranged in two Burkitt's lymphoma cell lines with either a t(2;8)(p12;q24) or t(8;22)(q24;q11). Alterations of MLV14 may have prognostic significance in some types of B-cell malignancies.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Blotting, Southern
Burkitt Lymphoma / genetics*
Chromosomes, Human, Pair 2*
Chromosomes, Human, Pair 22*
Chromosomes, Human, Pair 8*
Genes, myc / genetics
Genetic Markers / genetics
Humans
Prognosis
Translocation, Genetic / genetics*
Tumor Cells, Cultured

Substances

Genetic Markers