Generation of viable cholesterol-free mice

Science. 2003 Dec 19;302(5653):2087. doi: 10.1126/science.1090776.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue
  • Animals
  • Bile Acids and Salts / biosynthesis
  • Cholesterol / blood
  • Cholesterol / deficiency*
  • Cholesterol / metabolism
  • Cholesterol / physiology*
  • Desmosterol / metabolism*
  • Female
  • Gene Targeting
  • Growth
  • Humans
  • Infertility
  • Liver / metabolism
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Models, Animal
  • Nerve Tissue Proteins / genetics*
  • Nerve Tissue Proteins / metabolism
  • Oxidoreductases Acting on CH-CH Group Donors / genetics*
  • Oxidoreductases Acting on CH-CH Group Donors / metabolism
  • Phenotype
  • Sex Characteristics
  • Testis / pathology

Substances

  • Bile Acids and Salts
  • Nerve Tissue Proteins
  • Desmosterol
  • Cholesterol
  • Oxidoreductases Acting on CH-CH Group Donors
  • 3beta-hydroxysterol delta24-reductase
  • DHCR24 protein, human
  • Dhcr24 protein, mouse