Abstract
The frequency of individual genotypes GSTM1, GSTT1, and GSTP1 and haplotypes was determined in patients with atopic dermatitis and healthy children. The actual frequency of some haplotypes was far below the theoretical value. Some haplotypes were associated with predisposition and resistance to atopic dermatitis.
MeSH terms
-
Adolescent
-
Alleles
-
Case-Control Studies
-
Child
-
Child, Preschool
-
Dermatitis, Atopic / epidemiology
-
Dermatitis, Atopic / genetics*
-
Female
-
Gene Frequency
-
Genetic Predisposition to Disease*
-
Genotype*
-
Glutathione S-Transferase pi
-
Glutathione Transferase*
-
Haplotypes
-
Humans
-
Infant
-
Isoenzymes*
-
Male
-
Odds Ratio
-
Polymorphism, Genetic
-
Russia / epidemiology
Substances
-
Isoenzymes
-
glutathione S-transferase T1
-
GSTP1 protein, human
-
Glutathione S-Transferase pi
-
Glutathione Transferase
-
glutathione S-transferase M1