Abstract
We describe the third case (to our knowledge) of multiple basal cell carcinoma associated with myotonic dystrophy and carry out a genetic study of the tumor comparing it with healthy skin. We consider that our results show that this association might be not a purely random phenomenon and that the particular genetic characteristics of this disorder might have a role in the pathogenesis of the tumor.
MeSH terms
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Adult
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Carcinoma, Basal Cell / complications
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Carcinoma, Basal Cell / diagnosis
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Carcinoma, Basal Cell / genetics*
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Diagnosis, Differential
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Eyelids
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Face
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Genetic Counseling
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Humans
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Male
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Mosaicism / genetics*
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Myotonic Dystrophy / complications
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Myotonic Dystrophy / genetics*
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Neoplasms, Second Primary / complications
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Neoplasms, Second Primary / diagnosis
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Neoplasms, Second Primary / genetics*
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Protein Kinases / genetics
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Skin Neoplasms / complications
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Skin Neoplasms / diagnosis
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Skin Neoplasms / genetics*
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Thorax
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Trinucleotide Repeat Expansion