Screening-detected breast cancer in a man with BRCA2 mutation: case report

Radiology. 2004 Feb;230(2):553-5. doi: 10.1148/radiol.2302030360.

Abstract

Current indications for breast cancer screening in the male population are lacking, although family history of breast cancer may be such an indication. The authors describe a man with a history of clinically diagnosed right breast cancer who subsequently tested positive for the breast cancer susceptibility gene BRCA2 and received a diagnosis of mammographically detected left breast cancer at screening. The authors discuss the clinical implications of this approach to detecting male breast cancer.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • BRCA2 Protein / genetics*
  • Biopsy, Needle
  • Breast / pathology
  • Breast Neoplasms, Male / diagnostic imaging
  • Breast Neoplasms, Male / genetics*
  • Breast Neoplasms, Male / pathology
  • Breast Neoplasms, Male / therapy
  • Carcinoma, Ductal, Breast / diagnostic imaging
  • Carcinoma, Ductal, Breast / genetics*
  • Carcinoma, Ductal, Breast / pathology
  • Carcinoma, Ductal, Breast / therapy
  • Carcinoma, Lobular / diagnostic imaging
  • Carcinoma, Lobular / genetics*
  • Carcinoma, Lobular / pathology
  • Carcinoma, Lobular / therapy
  • Follow-Up Studies
  • Germ-Line Mutation*
  • Humans
  • Male
  • Mass Screening*
  • Mastectomy
  • Neoplasm Staging
  • Neoplasms, Hormone-Dependent / diagnostic imaging
  • Neoplasms, Hormone-Dependent / genetics
  • Neoplasms, Hormone-Dependent / pathology
  • Neoplasms, Hormone-Dependent / therapy
  • Neoplasms, Multiple Primary / diagnostic imaging
  • Neoplasms, Multiple Primary / genetics*
  • Neoplasms, Multiple Primary / pathology
  • Neoplasms, Multiple Primary / therapy
  • Radiography
  • Receptors, Estrogen / analysis
  • Receptors, Progesterone / analysis
  • Reoperation
  • Sentinel Lymph Node Biopsy

Substances

  • BRCA2 Protein
  • Receptors, Estrogen
  • Receptors, Progesterone