Abstract
In order to investigate the role of MBL gene polymorphisms in susceptibility to tuberculosis (TB) we genotyped 487 TB cases and 232 controls. Among African-American individuals, the frequency of B allele was lower among controls than cases (p < 0.01), but we found no differences between cases and controls of white and Hispanic ethnicity.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Aged
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Black or African American / genetics
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Case-Control Studies
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DNA, Bacterial / analysis
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Disease Susceptibility
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Female
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Genetic Predisposition to Disease*
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Hispanic or Latino / genetics
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Humans
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Incidence
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Male
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Mannose-Binding Lectin / genetics*
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Middle Aged
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Polymerase Chain Reaction
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Polymorphism, Genetic*
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Probability
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Reference Values
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Risk Assessment
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Sampling Studies
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Sensitivity and Specificity
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Tuberculosis, Pulmonary / ethnology*
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Tuberculosis, Pulmonary / genetics*
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United States / epidemiology
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White People / genetics
Substances
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DNA, Bacterial
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Mannose-Binding Lectin