Seafood allergy

Curr Opin Allergy Clin Immunol. 2004 Jun;4(3):231-4. doi: 10.1097/00130832-200406000-00016.

Abstract

Purpose of review: Given the importance and prevalence of seafood in our economy and diet, interest in the adverse effects of seafood-induced allergic reactions has increased both in the lay population and the scientific arena. The purpose for this review article is to provide an overview and discussion of current seafood-allergy research.

Recent findings: Current research has produced the discovery of new seafood allergens as well as a better understanding of the interactions of allergens with the host, and the relationships of IgE antibodies with specific allergens. Crossreactivity of similar molecules from seafood and nonseafood sources provides a better understanding of an allergen's role in seafood allergy and a basis to improve patient identification and treatment.

Summary: Findings in recent literature show potential for more precise diagnosis and safer, more effective treatment of seafood allergies.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cross Reactions / immunology
  • Food Hypersensitivity / etiology
  • Food Hypersensitivity / immunology*
  • Food Hypersensitivity / therapy
  • Humans
  • Immunoglobulin E / immunology
  • Interleukin-12 / therapeutic use
  • Seafood / adverse effects*

Substances

  • Interleukin-12
  • Immunoglobulin E