Abstract
ETS-1 in ovarian endometriomas was significantly positively correlated with microvessel counts (MVCs), but ETS-1 and MVC were not significantly altered during the menstrual cycle. Because ETS-1 persistently expresses in the subepithelial area of endometriotic endometrium, this might contribute to the growth of ovarian endometriomas via subepithelial angiogenesis independently of the menstrual cycle.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Endometriosis / genetics*
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Endometriosis / pathology
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Endometriosis / surgery
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Factor VIII / analysis
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Female
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Gene Expression Regulation / genetics*
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Humans
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Immunohistochemistry
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Microcirculation / pathology
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Neovascularization, Pathologic / genetics*
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Ovarian Diseases / genetics*
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Ovarian Diseases / pathology
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Ovarian Diseases / surgery
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Proto-Oncogene Protein c-ets-1
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Proto-Oncogene Proteins / genetics*
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Proto-Oncogene Proteins c-ets
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Reference Values
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Transcription Factors / genetics*
Substances
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ETS1 protein, human
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Proto-Oncogene Protein c-ets-1
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-ets
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Transcription Factors
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Factor VIII