Abstract
The authors studied the association between APOE-epsilon4 genotype and axis I and II psychiatric disorders an average of 30 years after traumatic brain injury. Sixty patients were dichotomized into subjects with and without APOE-epsilon4 allele. Dementia and subclinical dementia were significantly more common with the presence of APOE-epsilon4. The occurrence of other psychiatric disorders did not differ between patients with and without APOE-epsilon4 allele.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Alleles
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Amnesia / epidemiology
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Amnesia / etiology
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Apolipoprotein E4
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Apolipoproteins E / genetics*
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Brain Injuries / complications*
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Brain Injuries / epidemiology
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Dementia / epidemiology
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Dementia / etiology
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Dementia / genetics*
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Female
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Finland / epidemiology
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Gene Frequency
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Genetic Predisposition to Disease
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Genotype
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Humans
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Male
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Mental Disorders / complications
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Mental Disorders / epidemiology
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Mental Disorders / genetics
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Middle Aged
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Neuropsychological Tests
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Risk Factors
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Time Factors
Substances
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Apolipoprotein E4
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Apolipoproteins E