Abstract
The implication of MALT1 gene in the pathogenesis of primary cutaneous marginal zone B-cell lymphomas (PCMZL) has been a matter of controversy. We examined the presence of MALT1 translocations in a series of 23 PCMZL. FISH assay with a MALT1 dual color break apart translocation probe revealed the absence of MALT1 translocations in all cases.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Caspases
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Chromosomes, Human, Pair 14 / genetics
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Chromosomes, Human, Pair 14 / ultrastructure*
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Chromosomes, Human, Pair 18 / genetics
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Chromosomes, Human, Pair 18 / ultrastructure*
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Female
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Humans
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In Situ Hybridization, Fluorescence
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Lymphoma, B-Cell / genetics*
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Lymphoma, B-Cell, Marginal Zone / genetics*
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Lymphoma, Non-Hodgkin / genetics*
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Male
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Middle Aged
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Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
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Neoplasm Proteins / genetics*
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Skin Neoplasms / genetics*
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Translocation, Genetic*
Substances
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Neoplasm Proteins
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Caspases
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MALT1 protein, human
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Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein