Morphinome--proteome of the nervous system after morphine treatment

Amino Acids. 2005 Feb;28(1):13-9. doi: 10.1007/s00726-004-0144-y. Epub 2004 Dec 9.

Abstract

Proteome is a natural consequence of the post-genome era when the HUGO project (Human Genome Organization) has almost been completed. Here, a specifically aimed proteome in drug dependence--morphinome, is described, including tasks, strategies and pitfalls of the methodology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Culture Techniques / methods
  • Computational Biology
  • Disease Models, Animal
  • Humans
  • Morphine / pharmacology*
  • Morphine Dependence / metabolism*
  • Nervous System / drug effects*
  • Nervous System / metabolism*
  • Proteomics / methods*

Substances

  • Morphine