VBASE2, an integrative V gene database

Nucleic Acids Res. 2005 Jan 1;33(Database issue):D671-4. doi: 10.1093/nar/gki088.

Abstract

The database VBASE2 provides germ-line sequences of human and mouse immunoglobulin variable (V) genes. It acts as an interconnecting platform between several existing self-contained data systems: VBASE2 integrates genome sequence data and links to the V genes in the Ensembl Genome Browser. For a single V gene sequence, all references to the EMBL nucleotide sequence database are provided, including references for V(D)J rearrangements. Furthermore, cross-references to the VBASE database, the IMGT database and the Kabat database are available. A DAS server allows the display of VBASE2 V genes within the Ensembl Genome Browser. VBASE2 can be accessed either by a web-based text query or by a sequence similarity search with the DNAPLOT software. VBASE2 is available at http://www.vbase2.org, and the DAS server is located at http://www.dnaplot.com/das.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Databases, Nucleic Acid*
  • Genes, Immunoglobulin*
  • Humans
  • Immunoglobulin Variable Region / genetics*
  • Mice
  • Systems Integration
  • User-Computer Interface

Substances

  • Immunoglobulin Variable Region