Abstract
In this study, the frequencies of the common hemochromatosis gene mutations were assessed in 75 Iranian subjects with chronic hepatitis B infection. We found that the major C282Y mutation was significantly more frequent in subjects infected with hepatitis B virus (4%) than in 194 control subjects (0%, P=.02; Fisher's exact test).
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Female
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Genetic Predisposition to Disease
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Hemochromatosis / complications*
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Hemochromatosis / genetics*
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Hemochromatosis Protein
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Hepatitis B, Chronic / complications*
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Hepatitis B, Chronic / genetics
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Histocompatibility Antigens Class I / genetics*
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Humans
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Iran
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Male
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Membrane Proteins / genetics*
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Mutation / genetics*
Substances
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HFE protein, human
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Hemochromatosis Protein
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Histocompatibility Antigens Class I
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Membrane Proteins