Proteasome function and pathological proteins in the pathogenesis of Parkinson's disease

MeSH terms

• Animals
• Apoptosis / drug effects
• Disease Models, Animal
• Dopamine / metabolism
• Humans
• Lewy Bodies / drug effects
• Lewy Bodies / metabolism
• Lewy Bodies / pathology
• Mutation
• Neurotoxins / pharmacology*
• Oxidopamine / pharmacology*
• Parkinson Disease / etiology*
• Parkinson Disease / genetics
• Parkinson Disease / metabolism
• Parkinson Disease / pathology
• Proteasome Endopeptidase Complex / metabolism*
• Proteasome Inhibitors
• Protective Agents / metabolism*
• Rats
• Substantia Nigra / pathology
• Ubiquitin-Protein Ligases / genetics