Abstract
We studied 13 extended-spectrum beta-lactamase (ESBL)-producing enteropathogenic Escherichia coli isolates from children suffering acute diarrhea in Uruguay. ESBL characterization in crude extracts showed a single band at pI 5.4. PCR amplification and sequencing data allowed identification of blaPER-2 and blaTEM-116. Retrospective analysis suggests that these strains were disseminated in the community, even if unnoticed, prior to their access to the hospital environment more than a decade ago.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Cephalosporin Resistance
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Child, Preschool
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Diarrhea / epidemiology*
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Diarrhea / microbiology*
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Escherichia coli / drug effects*
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Escherichia coli / enzymology
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Escherichia coli / genetics
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Escherichia coli / isolation & purification*
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Escherichia coli Infections / epidemiology
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Escherichia coli Infections / microbiology
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Escherichia coli Proteins / genetics*
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Escherichia coli Proteins / metabolism
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Humans
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Infant
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Polymerase Chain Reaction / methods
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Sequence Analysis, DNA
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Uruguay / epidemiology
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beta-Lactamases / genetics*
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beta-Lactamases / metabolism
Substances
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Anti-Bacterial Agents
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Escherichia coli Proteins
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beta-Lactamases
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beta-lactamase TEM-103, E coli
Associated data
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GENBANK/AJ786366
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GENBANK/AJ847362
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GENBANK/AJ847363
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GENBANK/AJ847364