Abstract
High frequency of B-RAF gene mutations has recently been identified in benign melanocytic nevi and melanoma. This review focuses on clinical studies that evaluate the role of B-RAF in melanocytic neoplasia.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Humans
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Melanoma / classification
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Melanoma / genetics*
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Mutation
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Nevus, Pigmented / genetics
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Proto-Oncogene Proteins B-raf / genetics*
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Skin Neoplasms / classification
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Skin Neoplasms / genetics*
Substances
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BRAF protein, human
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Proto-Oncogene Proteins B-raf