Structure of the O-polysaccharide and serological studies of the lipopolysaccharide of Proteus mirabilis 2002

Carbohydr Res. 2005 Oct 17;340(14):2305-10. doi: 10.1016/j.carres.2005.07.014.

Abstract

The structure of the O-polysaccharide of the lipopolysaccharide of Proteus mirabilis 2002 was elucidated by chemical methods and 1H and 13C NMR spectroscopy. It was found that the polysaccharide consists of branched pentasaccharide repeating units having the following structure: [structure in text]. The O-polysaccharide of P. mirabilis 2002 has a common tetrasaccharide fragment with that of P. mirabilis 52/57 from serogroup O29, and the lipopolysaccharides of the two strains are serologically related. Therefore, based on the structural and serological data, we propose to classify P. mirabilis 2002 into the Proteus O29 serogroup as a subgroup O29a,29b.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Carbohydrate Sequence
  • Immune Sera
  • Lipopolysaccharides / chemistry*
  • Lipopolysaccharides / immunology
  • Magnetic Resonance Spectroscopy
  • Molecular Sequence Data
  • Proteus mirabilis / growth & development
  • Proteus mirabilis / immunology*
  • Rabbits

Substances

  • Immune Sera
  • Lipopolysaccharides