Abstract
Although cadherins and catenins are known to play important roles during neural development, the types of alpha-catenin present in the developing telencephalon are still unknown. Here, we show that the ventricular zones (VZ) of the cortex and the ganglionic eminences express alphaE-catenin and alphaN-catenin, respectively, in a complementary manner. In the cortex, alpha-catenin is switched from alphaE-catenin in the VZ to alphaN-catenin II in the intermediate zone (IMZ).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Differentiation / physiology*
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Cell Movement / physiology
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Cerebral Cortex / cytology
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Cerebral Cortex / embryology*
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Cerebral Cortex / metabolism*
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Choroid Plexus / cytology
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Choroid Plexus / embryology
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Choroid Plexus / metabolism
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Immunohistochemistry
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Interneurons / cytology
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Interneurons / metabolism
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Lateral Ventricles / cytology
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Lateral Ventricles / embryology
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Lateral Ventricles / metabolism
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Mice
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Nerve Tissue Proteins / metabolism*
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Neural Inhibition / physiology
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Neurons / cytology
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Neurons / metabolism*
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Stem Cells / cytology
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Stem Cells / metabolism*
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alpha Catenin / metabolism*
Substances
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Ctnna2 protein, mouse
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Nerve Tissue Proteins
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alpha Catenin