Leucine-rich repeat kinase 2: a new player with a familiar theme for Parkinson's disease pathogenesis

Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16535-6. doi: 10.1073/pnas.0508350102. Epub 2005 Nov 7.

Authors

Chenjian Li¹, M Flint Beal

Affiliation

¹ Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA. chl2011@med.cornell.edu

No abstract available

Publication types

Comment

MeSH terms

Genes, Dominant
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Mitochondria / enzymology
Mitochondria / physiology
Mutation
Parkinson Disease / enzymology*
Parkinson Disease / etiology
Parkinson Disease / physiopathology
Protein Serine-Threonine Kinases / chemistry
Protein Serine-Threonine Kinases / genetics
Protein Serine-Threonine Kinases / metabolism*
Substrate Specificity

Substances

LRRK2 protein, human
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Protein Serine-Threonine Kinases