Congenital indifference to pain and deletion of chromosome 10q-: new association

J Child Neurol. 2006 Feb;21(2):174-7. doi: 10.1177/08830738060210022001.

Abstract

We describe a case of a de novo terminal deletion of the long arm of chromosome 10 with the novel feature of congenital indifference to pain in a 2-year 10-month-old boy. Relative indifference to pain defined by a lack of emotional response to pain has not been described previously in association with the terminal deletion of the long arm of chromosome 10.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Chromosome Banding
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 10*
  • Developmental Disabilities / diagnosis
  • Developmental Disabilities / genetics
  • Ear, External / abnormalities
  • Emotions
  • Esotropia / diagnosis
  • Esotropia / genetics
  • Follow-Up Studies
  • Humans
  • Hypesthesia / diagnosis
  • Hypesthesia / genetics*
  • Infant
  • Infant, Newborn
  • Karyotyping
  • Male
  • Muscle Hypotonia / diagnosis
  • Muscle Hypotonia / genetics