Coexistent Marfan's syndrome and ankylosing spondylitis

Csaba Kiss; Ildiko Jónap; Peter Gergely; Gyula Poór

Coexistent Marfan's syndrome and ankylosing spondylitis

J Rheumatol. 2006 Jun;33(6):1199-200.

Authors

Csaba Kiss¹, Ildiko Jónap, Peter Gergely, Gyula Poór

Affiliation

¹ National Institute of Rheumatology and Physiotherapy, 1st Department of Rheumatology, Budapest, Hungary. kiss.csaba@mail.orfi.hu

PMID: 16755670

Abstract

We describe a 22-year-old woman with coexisting Marfan's syndrome (MFS) and ankylosing spondylitis (AS). A change of fibrillin-1 due to mutation of the FBN1 gene (MFS) or a cell-mediated autoimmune response in AS could account for a common pathology.

Publication types

Case Reports

MeSH terms

Adult
Echocardiography
Female
Fibrillin-1
Fibrillins
Humans
Marfan Syndrome / complications*
Marfan Syndrome / diagnosis
Marfan Syndrome / metabolism
Microfilament Proteins / genetics
Microfilament Proteins / metabolism
Mutation
Spondylitis, Ankylosing / complications*
Spondylitis, Ankylosing / diagnosis

Substances

FBN1 protein, human
Fibrillin-1
Fibrillins
Microfilament Proteins