[Association of the IVS9-675C > A polymorphism of the HIF-1alpha gene with acute ischemic stroke in the Moscow population]

T V Tupitsyna; P A Slominskiĭ; M I Shadrina; I M Shetova; V I Skvortsova; S A Limborskaia

[Association of the IVS9-675C > A polymorphism of the HIF-1alpha gene with acute ischemic stroke in the Moscow population]

Genetika. 2006 Jun;42(6):858-61.

[Article in Russian]

Authors

T V Tupitsyna, P A Slominskiĭ, M I Shadrina, I M Shetova, V I Skvortsova, S A Limborskaia

PMID: 16871792

Abstract

The IVS9-675C > A polymorphism of the HIF-1alpha gene was analyzed in patients with acute ischemic stroke and in a control group. The genotype and allele frequencies proved to significantly differ between the two groups. Allele C and genotypes containing this allele were associated with a higher risk of stroke in the Moscow population.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Acute Disease
Alleles
Humans
Hypoxia-Inducible Factor 1, alpha Subunit / genetics*
Intracranial Arteriosclerosis / blood
Intracranial Arteriosclerosis / genetics*
Intracranial Thrombosis / blood
Intracranial Thrombosis / genetics*
Moscow
Polymorphism, Genetic*
Risk Factors

Substances

HIF1A protein, human
Hypoxia-Inducible Factor 1, alpha Subunit