Association of interleukin-10 gene promoter polymorphism in children with atopic dermatitis

Myung Hyun Sohn; Jae Seok Song; Kyung-Won Kim; Eun-Soo Kim; Kyu-Earn Kim; Jae Myun Lee

doi:10.1016/j.jpeds.2006.08.065

Association of interleukin-10 gene promoter polymorphism in children with atopic dermatitis

J Pediatr. 2007 Jan;150(1):106-8. doi: 10.1016/j.jpeds.2006.08.065.

Authors

Myung Hyun Sohn¹, Jae Seok Song, Kyung-Won Kim, Eun-Soo Kim, Kyu-Earn Kim, Jae Myun Lee

Affiliation

¹ Department of Pediatrics, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.

PMID: 17188628
DOI: 10.1016/j.jpeds.2006.08.065

Abstract

The present study evaluated the possible role of interleukin (IL)-10 promoter polymorphisms in children with atopic dermatitis (AD). IL-10 promoter polymorphisms are associated with the phenotype of AD in children.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Antibodies, Anti-Idiotypic
Biomarkers / blood
Child
DNA / genetics*
Dermatitis, Atopic / blood*
Dermatitis, Atopic / genetics
Dermatitis, Atopic / immunology
Eosinophils / pathology
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Immunoglobulin E / immunology
Interleukin-10 / blood
Interleukin-10 / genetics*
Leukocyte Count
Male
Polymerase Chain Reaction
Polymorphism, Genetic*
Promoter Regions, Genetic / genetics*

Substances

Antibodies, Anti-Idiotypic
Biomarkers
Interleukin-10
Immunoglobulin E
DNA