Abstract
Leptin, a peptide secreted by the white adipose tissue, circulates to the central nervous system and signals the status of body energy stores, regulating feeding behavior and energy balance. As human obesity is characterized by hyperleptinemia and leptin resistance, increasing leptin sensitivity is an attractive target for obesity treatment.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Humans
-
Leptin / genetics
-
Leptin / physiology*
-
Leptin / therapeutic use
-
Lipid Metabolism
-
Obesity / drug therapy
-
Obesity / physiopathology
-
Recombinant Proteins / genetics
-
Recombinant Proteins / metabolism
-
Recombinant Proteins / therapeutic use
-
Signal Transduction
Substances
-
Leptin
-
Recombinant Proteins