Abstract
In the present study, we investigate intestinal alkaline phosphatase activity in mucosal biopsies in patients with inflammatory bowel disease. Crohn's disease influences the alkaline phosphatase activity in the intestine, increasing its activity. We present a histochemistry-based method for alkaline phosphatase that is useful for the identification of Crohn's disease and the differentiation of ulcerative colitis.
MeSH terms
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Alkaline Phosphatase
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Antigens, Neoplasm / analysis*
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Colitis, Ulcerative / diagnosis*
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Colitis, Ulcerative / enzymology
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Colitis, Ulcerative / pathology
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Crohn Disease / diagnosis*
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Crohn Disease / enzymology
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Crohn Disease / pathology
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Diagnosis, Differential
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GPI-Linked Proteins
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Histocytochemistry / methods*
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Humans
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Intestinal Mucosa / enzymology*
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Intestinal Mucosa / pathology
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Predictive Value of Tests
Substances
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Antigens, Neoplasm
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GPI-Linked Proteins
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ALPI protein, human
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Alkaline Phosphatase