Killer cell Ig-like receptors CD158a and CD158b display a coactivatory function, involving the c-Jun NH2-terminal protein kinase signaling pathway, when expressed on malignant CD4+ T cells from a patient with Sezary syndrome

Blood. 2007 Jun 1;109(11):5064-5. doi: 10.1182/blood-2007-02-071993.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • CD3 Complex / biosynthesis
  • CD4-Positive T-Lymphocytes / immunology*
  • Cell Proliferation
  • Gene Expression Regulation*
  • Humans
  • Immunoglobulins / chemistry
  • JNK Mitogen-Activated Protein Kinases / chemistry*
  • Killer Cells, Natural / metabolism
  • Leukocytes, Mononuclear / cytology
  • Leukocytes, Mononuclear / metabolism
  • Receptors, Immunologic / biosynthesis*
  • Receptors, KIR
  • Receptors, KIR2DL1
  • Receptors, KIR2DL3
  • Sezary Syndrome / blood*
  • Sezary Syndrome / immunology*
  • Signal Transduction*

Substances

  • CD3 Complex
  • Immunoglobulins
  • Receptors, Immunologic
  • Receptors, KIR
  • Receptors, KIR2DL1
  • Receptors, KIR2DL3
  • JNK Mitogen-Activated Protein Kinases