The T1790A BRAF mutation (L597Q) in childhood acute lymphoblastic leukemia is a functional oncogene

Leukemia. 2007 Oct;21(10):2216-8. doi: 10.1038/sj.leu.2404761. Epub 2007 May 24.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Mice
  • Mutagenesis, Site-Directed
  • Mutation*
  • Mutation, Missense
  • NIH 3T3 Cells
  • Oncogenes / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Proto-Oncogene Proteins B-raf / genetics*
  • Proto-Oncogene Proteins B-raf / physiology*

Substances

  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf