Segmental uniparental disomy as a recurrent mechanism for homozygous CEBPA mutations in acute myeloid leukemia

Leukemia. 2007 Nov;21(11):2382-4. doi: 10.1038/sj.leu.2404795. Epub 2007 Jun 7.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • CCAAT-Enhancer-Binding Proteins / genetics*
  • DNA Mutational Analysis
  • Gene Deletion
  • Genome
  • Homozygote
  • Humans
  • Karyotyping
  • Leukemia, Myeloid, Acute / genetics*
  • Loss of Heterozygosity
  • Models, Genetic
  • Mutation*
  • Protein Structure, Tertiary
  • Uniparental Disomy*

Substances

  • CCAAT-Enhancer-Binding Proteins
  • CEBPA protein, human