Crystal structure of the Helicobacter pylori enoyl-acyl carrier protein reductase in complex with hydroxydiphenyl ether compounds, triclosan and diclosan

Proteins. 2007 Nov 15;69(3):691-4. doi: 10.1002/prot.21586.

Authors

Hyung Ho Lee¹, Jinho Moon, Se Won Suh

Affiliation

¹ Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.

PMID: 17879346
DOI: 10.1002/prot.21586

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry*
Anti-Bacterial Agents / metabolism
Crystallography, X-Ray
Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) / chemistry*
Halogenated Diphenyl Ethers
Helicobacter pylori / enzymology*
Models, Molecular
Phenyl Ethers / chemistry*
Phenyl Ethers / metabolism
Protein Binding
Protein Conformation
Triclosan / chemistry*
Triclosan / metabolism

Substances

Anti-Bacterial Agents
Halogenated Diphenyl Ethers
Phenyl Ethers
diclosan
Triclosan
Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)