Abstract
We designed a novel PCR-RFLP assay to genotype for the CXCR2 +1440 (G/A) single nucleotide polymorphism, which provides a simple, low-cost, practical, and reproducible method. Allele frequencies in healthy Brazilian individuals were found to be 0.65% for allele A and 0.35% for allele G.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles
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Amplified Fragment Length Polymorphism Analysis / methods
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Base Sequence
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Brazil
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Case-Control Studies
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DNA Primers / genetics
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Gene Frequency
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Humans
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Periodontal Diseases / genetics
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Periodontal Diseases / immunology
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Polymerase Chain Reaction / methods*
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Polymorphism, Restriction Fragment Length
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Polymorphism, Single Nucleotide*
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Receptors, Interleukin-8B / genetics*
Substances
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DNA Primers
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Receptors, Interleukin-8B