No association between vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) and the variability of warfarin dose requirement in a Japanese patient population

Thromb Res. 2008;122(2):179-84. doi: 10.1016/j.thromres.2007.09.015. Epub 2007 Nov 9.

Authors

Tong Yin¹, Hironori Hanada, Kotaro Miyashita, Yoshihiro Kokubo, Yasuhisa Akaiwa, Ryoichi Otsubo, Kazuyuki Nagatsuka, Toshiho Otsuki, Akira Okayama, Kazuo Minematsu, Hiroaki Naritomi, Hitonobu Tomoike, Toshiyuki Miyata

Affiliation

¹ Research Institute, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

PMID: 17996924
DOI: 10.1016/j.thromres.2007.09.015

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Amino Acid Sequence
Female
Haplotypes
Humans
Japan
Male
Middle Aged
Mixed Function Oxygenases / genetics*
Mixed Function Oxygenases / physiology
Molecular Sequence Data
Pharmacogenetics / methods*
Phenotype
Polymorphism, Single Nucleotide
Sequence Homology, Amino Acid
Vitamin K Epoxide Reductases
Warfarin / administration & dosage*

Substances

Warfarin
Mixed Function Oxygenases
VKORC1 protein, human
VKORC1L1 protein, human
Vitamin K Epoxide Reductases